Twin power calculator

This Shiny application provides automated power analysis for the detection of additive genetic (A) and common environmental (C) variance components of a quantitative trait in the classical twin design.


Adjust the parameters on the left and press calculate to view the results


Results

ACE vs. CE model
ACE vs. AE model




Definitions

NCP: Noncentrality parameter, ML: Maximum likelihood, E: Environmental variance component, MZ: Monozygotic, DZ: Dizygotic

If you use this site, please reference the following: Visscher P.M. (2004). 'Power of the classical twin design revisited'. Twin Research 7, 505-512 and Visscher P.M., Gordon S., Neale M.C. (2008) and 'Power of the classical twin design revisited: II Detection of Common Environmental Variance'. Twin Research and Human Genetics 11, 48-54.

Please send suggestions or comments to Peter Visscher or if you are having difficulties with the application please contact Luke Lloyd-Jones at l.lloydjones@uq.edu.au. This application was prepared by Matthew Robinson, Luke Lloyd-Jones and Peter Visscher.